[Non-Shedding]: Expertly machine-woven from enhanced soft synthetic durable fibers that have a virtually non-shedding pile
[Plush amp; Cozy]: Features a 2-inch pile height for just the right amount of cushioned softness underfoot
[Trendy Style]: Contemporary design beautifully enhances any room of the home, from the living room, dining room, bedroom, entryway, nursery, dorm room, study, home office, or eat-in kitchen
[Easy Maintenance]: Stress-free cleaning includes regular vacuuming (without a beater bar) and gently blotting out minor stains with a mild detergent or carpet cleaner
[Trusted Brand]: Safavieh has been a trusted brand and leader in home furnishings for over 100 years, using their specialty and expertise in crafting the trendiest and highest quality designs and selection of colors; Begin your rug search with Safavieh and explore over 100,000 products today
2020 Impact Factor: 9.941Submission > Acceptance: 52 days
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This open-label, single-arm study investigated the long-term efficacy of tafasitamab plus lenalidomide in 81 patients with relapsed/refractory diffuse large B-cell lymphoma. The response rate was 57.5%, including complete responses in 40.0% of patients, and the median duration of response was 43.9 months. This treatment is a valuable option for patients not eligible for autologous stem-cell transplantation.
Grey zone lymphoma is a B-cell lymphoma, unclassifiable, with features intermediate between those of large B-cell lymphoma and classic Hodgkin lymphoma. The in-depth study of the two adolescent patients described in this case report expands the clinicopathological and genomic spectrum of this rare pediatric disease. Moreover, it provides information on their response to treatment.
The clinical picture of 56 patients with congenital amegakaryocytic thrombocytopenia due to MPL mutations was much more varied than previously thought. Twenty-five per cent of them had no signs of thrombocytopenia at birth, and 50% had non-hematologic defects. Pancytopenia developed in (nearly) all patients and hematopoietic stem-cell transplantation was effective in 87% of cases.
Sickle red blood cells exhibit abnormal adhesion to laminin mediated by Lu/BCAM protein at their surface. This study provides evidence of the involvement of oxidative stress in post-translational modifications of Lu/BCAM which impact the protein’s distribution and cis-interaction with glycophorin C at the cell surface activating its adhesive function in dense sickle red cells. The authors speculate that antioxidant drugs might attenuate this phenomenon.